CALGARY, April 17 /PRNewswire-FirstCall/ – Oncolytics Biotech Inc.
(“Oncolytics”) (TSX:ONC, NASDAQ:ONCY) announces that a poster by Dr. Maureen
E. Lane et al. of Cornell University, New York, entitled “In Vivo Synergy
between Oncolytic Reovirus and Gemcitabine in Ras-Mutated Human HCT116
Xenografts” is scheduled to be presented today at the American Association for
Cancer Research (AACR) Annual Meeting in Los Angeles, CA. The meeting runs
from April 14-18, 2007.
The researchers found that treatment of human colon cancer cell lines with
the combination of REOLYSIN(R) and gemcitabine resulted in both in vitro and
in vivo synergy. There was no toxicity associated with the combined treatment.
Tumours treated with the combination were significantly smaller (by area and
weight) than tumours in control groups or tumours treated with either agent
alone. The researchers concluded that the synergistic combination of
REOLYSIN(R) and gemcitabine is a promising therapeutic regimen for study in
“It is rare to see the virtual elimination of tumours as well as the
long-lasting therapeutic effect that we have observed from this study,” said
Dr. Brad Thompson, President and CEO of Oncolytics. “We are very encouraged by
these results and look forward to testing this particular treatment
combination in our upcoming human systemic administration trial in the U.K.”
The poster will be available on the Oncolytics website today at
About Oncolytics Biotech Inc.
Oncolytics is a Calgary-based biotechnology company focused on the
development of oncolytic viruses as potential cancer therapeutics. Oncolytics’
clinical program includes a variety of Phase I and Phase II human trials using
REOLYSIN(R), its proprietary formulation of the human reovirus, alone and in
combination with radiation or chemotherapy. For further information about
Oncolytics, please visit www.oncolyticsbiotech.com.
This press release contains forward-looking statements, within the meaning
of Section 21E of the Securities Exchange Act of 1934, as amended.
Forward-looking statements, including the implication of the materials
presented at this conference with respect to REOLYSIN(R), the Company’s
expectations related to the results of trials investigating delivery of
REOLYSIN(R), and the Company’s belief as to the potential of REOLYSIN(R) as a
cancer therapeutic, involve known and unknown risks and uncertainties, which
could cause the Company’s actual results to differ materially from those in
the forward-looking statements. Such risks and uncertainties include, among
others, the availability of funds and resources to pursue research and
development projects, the efficacy of REOLYSIN(R) as a cancer treatment, the
success and timely completion of clinical studies and trials, the Company’s
ability to successfully commercialize REOLYSIN(R), uncertainties related to
the research and development of pharmaceuticals and uncertainties related to
the regulatory process. Investors should consult the Company’s quarterly and
annual filings with the Canadian and U.S. securities commissions for
additional information on risks and uncertainties relating to the
forward-looking statements. Investors are cautioned against placing undue
reliance on forward-looking statements. The Company does not undertake to
update these forward-looking statements.
SOURCE Oncolytics Biotech Inc.
Released April 17, 2007